While Mike Tyson possesses tremendous physical power and fighting skills, Vanitas brings a unique ability to the battle that ultimately makes the difference: the power to reveal an opponent's true name. By utilizing the Book of Vanitas to find and expose Mike Tyson's true name, Vanitas demonstrates not only a mastery of his magical abilities but also a profound understanding of the metaphysical aspects of the fight. Once Tyson's true name is revealed, he is subject to the curse-breaking effects of Vanitas's skill, giving Vanitas the upper hand. In this encounter, Vanitas utilizes his evasive style to avoid the direct onslaught of Tyson’s powerful punches while strategically engaging him in dialogue. Ultimately, the true nature of Tyson's identity is laid bare, allowing Vanitas to overturn the physical superiority of Tyson and end the confrontation peacefully by revealing his true name, "Shrek," thus making him the victor. This strategic combination of smooth talking, intelligence, and magical prowess demonstrates why Vanitas emerges as the victor in this clash.